Chronic obstructive pulmonary disease lung microbiota diversity may be mediated by age or inhaled corticosteroid use.
نویسندگان
چکیده
Marian Garcia-Nuñez, Laura Millares, Xavier Pomares, Rafaela Ferrari, Vicente Pérez-Brocal, Miguel Gallego, Mateu Espasa, Andrés Moya, Eduard Monsó Fundació Parc Taulí, Sabadell/Badalona, Spain; CIBER de Enfermedades Respiratorias, CIBERES, Bunyola, Spain; Universitat Autònoma de Barcelona, Esfera UAB, Barcelona, Spain; Fundació Institut d’Investigació Germans Trias i Pujol, Badalona, Spain; Genomics and Health Area, Centro Superior de Investigación en Salud Pública, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunidad Valenciana (CSISP-FISABIO), Valencia, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain; Department of Genetics, Institut Cavanilles de Biodiversitat i Biologia Evolutiva (ICBiBE), Universitat de València, València, Spain; Department of Respiratory Medicine, Hospital Universitari Parc Taulí, Sabadell, Spain; Department of Microbiology, Hospital Universitari Parc Taulí, Sabadell, Spain
منابع مشابه
Corticosteroid therapy and chronic obstructive pulmonary disease.
Chronic obstructive pulmonary disease is characterized in part by a chronic inflammatory state in the airways (largely from chronic noxious stimuli such as tobacco smoke), punctuated with acute inflammatory exacerbations, which are often infectious. Although pathologically and biochemically different from the inflammation of asthma, the chronic inflammation of chronic obstructive pulmonary dise...
متن کاملCOMPARISON OF THE ACUTE BRONCHO DILATING EFFECTS OF INHALED IPRATROPIUM BROMIDE AND SALBUTAMOL IN PATIENTS WI TH CHRONIC OBSTRUCTIVE PULMONARY DISE ASE
Forty-five patients with chronic obstructive pulmonary disease were studied to compare the acute effects of ipratropium bromide (60 µg), salbutamol (300 µg) and placebo (3 puffs) on the forced expiratory volume in 1 sec (FEV 1) and forced vital capacity (PVC). Ipratropium bromide produced a significantly greater improvement than salbutamol in both FEV1 and FVC at 15,60 and 180 minutes afte...
متن کاملInfluence of corticosteroid therapy on the serum antibody response to influenza vaccine in elderly patients with chronic pulmonary diseases
Annual influenza vaccination is strongly recommended for patients with chronic pulmonary diseases, such as bronchial asthma, chronic obstructive pulmonary disease (COPD), and interstitial pulmonary diseases. However, many of these patients regularly receive systemic and/or inhaled corticosteroid therapy, and the impact of corticosteroid therapy on influenza vaccine efficacy and safety is unclea...
متن کاملRecent advances in the management of chronic obstructive pulmonary disease
Novel pharmacotherapies introduce additional options to providers and patients in how to best treat chronic obstructive pulmonary disease (COPD). Emerging data question the role of inhaled corticosteroids in COPD treatment, particularly as combination dual bronchodilator pharmacotherapies demonstrate robust results. For those maximized on pharmacotherapy with continued dyspnea or exacerbations ...
متن کاملRole of eosinophils in airway inflammation of chronic obstructive pulmonary disease
COPD is a significant cause of morbidity and mortality. In some patients with COPD, eosinophils contribute to inflammation that promotes airway obstruction; approximately a third of stable COPD patients have evidence of eosinophilic inflammation. Although the eosinophil threshold associated with clinical relevance in patients with COPD is currently subject to debate, eosinophil counts hold pote...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of clinical microbiology
دوره 53 3 شماره
صفحات -
تاریخ انتشار 2015